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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e94f8726c4a61d9b174c63e9b35a01485ec7fb7041afba6eb5e6992b308762d4' 
  AND token = '+R4ybnfE7yd72CXlDPuylHit40kc6cUjJJLTcIivtSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}