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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3a260210e27351e4df72494759ca0ba091ee3e4ceb138fec47521ee06d3be3' 
  AND token = '2/ib6oWI53xC6Grx0Ay9Ti5ByqIJzLFuZGn5Nn0fwdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}