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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65de84b4a4679ad3eaae207bb805240bc1ee62b42fcdd059fdd1569e37dca01' 
  AND token = '/QE0FZQWCBhY5QH51LBKZbMlbVs+108nwSaN+jXH+SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}