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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a84b0ce872b40972067ef0669e556dddc68879a2b08a171274ffdf4f0c9247bd' 
  AND token = 'EdxBl1qGSSZxG7SpTeb1+wt1SAZksDdZiuXnBLqggMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}