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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2365565569fb633fc87256bfeca2d0d58acb06caf82e2d35804121e4b3a90dc' 
  AND token = '+lXzXo777hX0fvhOXnfLsgjgwsnpljjiHbiaQ5kF0KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}