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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb9225df99c45c53336d63c84c90656fd0d0b881d52e01e6d2e2cef41eee4f9' 
  AND token = 'HI6KVWmIcA6yCPhnyBSFQBTCFAeJXZvdnbqqrYgmcXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}