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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c74d63eda1bb6795e4a45f1fe56a83006293902ff67a16b04d6d251705fb3071' 
  AND token = 'yv51Syz/2KJ3CxTDJ60YG30pcgCmPYcVqfMMmvV2kVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}