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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e9ed4e98fcaa60a981a819871a7c5efae18132373eaf3ded3d0db18f1fd39b5' 
  AND token = 'vsOkvauj5TQzDhCUBN02OMrT9SI6vrR43vNsBxPgJI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}