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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db53333afbe1268a149c82b506324fbcdb0af7132783ea9f63a802f43d2bc203' 
  AND token = 'pHlRuLI0yiAJOmzbo7AbZYRootQqL921UvY+Nfvbu+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}