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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b66030f03f58475963b79504bb33c6dacb745a11e03abf5ae911bced7d3740f' 
  AND token = '1MCuYpoom6iViKW0RK6vHDITgAKDh5BKJ21bkb2zrRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}