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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f72af817b13294435f474737c0a1badc6b97c3aa48d4d9b828cacfb902ccd03' 
  AND token = '463JxdQXO95Uxd1F447/vpcXTs9GAo4hI0U7nxsZzmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}