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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '025150330930b451530f32a6f6c5394028143451520224da79f0f76f3aaa68fe' 
  AND token = '73YN62nPOShnpXGPBIBt57RJd9d9vkZJkMLHVl3/XSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}