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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a5d3f58d7bd318ba1399c2942d39b200514a21eeb4b67d644ddd633f010f88a' 
  AND token = 'Wx5zwgW5q5AkqfoAp13wA/jtMnCxzJmV4uFFijei+qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}