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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d2935042b05f12033c5b0c2eb7f4f23bad6b16a154fa7ec26da882e2d14092' 
  AND token = 'ivcDdUqMBYs7ufYeS+mM4fuUnTDdJ0Fq0SoERp6Qark=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}