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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1e3e0ed887b87284ffe493e7f6a0be069aab0fe7ef7d7e9d3b71916e787fef' 
  AND token = 'nEX9dxX2sBHrOvlQ5v2FdgFeuKV2NTp9FpXxXw0eQCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}